iVF Riga Centre for Biotechnology and Stem Cells recommends creating a child’s genetic passport
when collecting stem cells from the umbilical cord blood. If there is suspicion of a genetic disease, genetic research allows to carry out the appropriate tests to confirm or exclude the possible diagnosis. These tests allow to determine disease predisposition, and, based on the DNA analysis, determine its origin; in addition, genetic tests allow the doctors to choose the right treatment approach, as well as calculate the risk, which is related to the repeated occurrence of the disease in the family. In some cases, early diagnosis can prevent the disease from manifestation. iVF Riga Centre for Biotechnology and Stem Cells Riga offers the following services for creating a comprehensive genetic passport: Expanded versions of Lux
programs for extraction and storage of stem cells found in the umbilical cord blood. These programs include molecular genetic testing, which is carried out in a specialized reproductive genetics laboratory. These tests allow to determine whether the person is a carrier of the following diseases:
- Coeliac disease. Timely diagnosis of hereditary gluten intolerance.
- Hereditary lactose intolerance. Lactose intolerance is a metabolic food disorder, which is associated with the deficiency of an enzyme lactase. The lack of lactase means that lactose cannot be digested and absorbed.
- Cystic fibrosis – hereditary genetic disorder, which is caused by various mutations in the CFTR gene. This disorder affects exocrine glands, the respiratory system, as well as the stomach and the digestive system.
- Hereditary hemochromatosis – hereditary, genetically caused disorder, which is characterized by excessive accumulation of iron in the body’s tissues and organs, thus leading to organ toxicity.
- Hereditary alpha 1-antytripsin deficiency, which manifests as pulmonary emphysema, liver cirrhosis and, rarely, as the skin disease panniculitis. The hereditary alpha 1-antytripsin deficiency is particularly dangerous for smokers, as due to lung breakdown, their life expectancy decreases dramatically.