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Centre for Reproductive Genetics

The number of embryos examined for the presence of genetic abnormalities: 2616

The number of IVF cycles after PGD (or PGT-M, Preimplantation genetic testing for monogenic/single gene diseases): 8 *

* for the families after genetic examination, in which the hereditary genetic disorder is molecularly confirmed. Currently iVF Riga Clinic has embryos tested for the following genetic abnormalities:

  • Huntington’s chorea – mutations in the HTT gene;
  • Thoracic Aortic Dissections – mutations in the ACTA2 gene;
  • Ichthyosis - mutations in the ALOX12B gene;
  • Neuronal ceroid lipofuscinosis – mutations in the TPP1 gene;
  • GM1-Gangliosidosis – mutations in the GLB1 gene;
  • Myotubular myopathy – mutations in the MTM1 gene;
  • Duchenne and Becker muscular dystrophy – mutations in the DMD gene

iVF Riga Genetic Center

In 2014, iVF Riga opened the first Genetic Center in Northern Europe, where you can get in-depth genetic examinations.

We are the only clinic in Latvia who performs Preimplantation genetic testing on site, in our own laboratory. We perform PGT-A and PGT-M testing for other Latvian and foreign clinics. All other Latvian clinics send the material abroad.

Genetic counselling is important for couples who are just planning to become parents. Genetic counseling is recommended if:

Your family has a history of children born with malformations, mental or physical retardation, genetic diseases, stillbirth child, and history of consanquinity

You should be more considered of the health of a child due to later pregnancy (after 35), as adverse effects (mother’s illness, medications, physical and chemical factors) on the fetus  are common.

Genetic Laboratory of the iVF Riga Center for Reproductive Genetics currently provides additional testing for the following diseases:

  • Coeliac disease. Timely diagnosis of genetic predisposition to gluten intolerance.
  • Congenital lactose intolerance diagnostication.
  • Ichthyosis — congenital skin condition when the epidermis becomes dry and rough due to excessive keratin production.
  • Hereditary hemochromatosis – hereditary, genetically caused disorder, which is characterized by excessive accumulation of iron in the body’s tissues and organs, including men's testicular tissues. Excessive iron accumulation can cause a gradual cessation of spermatogenesis.

  • Alpha‑1-antitrypsin deficiency, which leads to a violation of the elasticity and strength of the structural elements of the lungs and as a result — the development of emphysema. Alpha‑1-antitrypsin deficiency is particularly dangerous for smokers: their lifetime significantly reduces due to lung deterioration.

  • Recessive sensorineural hearing loss. Analysis of the most common GJB2 gene mutations, which lead to congenital hearing loss.
  • Spinal muscular atrophy (SMA) carrier testing with MLPA (SMN1 and SMN2 deletion carrier testing).

Genetic Counseling and Examinations

In our clinic, patients consult geneticists Dr. Liene Kornejeva; Dr. Ieva Grinfelde

It is important for patients with ongoing pregnancy to undergo genetic counseling if:
  • One of the family members has a known genetic disease or confirmed chromosomal abnormality
  • History of one or more spontaneous abortions
  • Structural abnormalities of the fetus have been found during ongoing pregnancy
  • There have been changes in first trimester screening
  • Congenital or chromosomal diseases of the fetus have been found

What is genetic screening?

Genetic screening is a precise and well-timed discovery of possible genetic disorders in a fetus (Down syndrome etc.). Persons with positive or suspicious results are sent to the doctor to establish a diagnosis and further treatment tactics.

Who is in the high risk group?

A patient in the risk group is one for whom there is a higher possibility that any of pregnancy/fetal/childbirth pathologies will develop than for others. It does not mean that if the patient belongs to risk group, pathology will definitely develop, although during prenatal care it is important to pay special attention to diagnoses of pathologies in proper time to prevention of pregnancy complications.

At the same time, patients who do not fit in the risk group may develop prenatal/fetal/childbirth pathologies, but the risk is significantly lower.

Contact our patient's coordinators!
Jelena Silkalna
Jelena Silkalna
Marina Valetko
Marina Valetko
Nadia Hrolenko (ex Runce)
Nadia Hrolenko (ex Runce)
Zita Gaidule (on maternity leave)
Zita Gaidule (on maternity leave)
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